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成都地区脑瘫儿童粗大运动功能分级与脑瘫高危因素的相关性分析
Correlation Between Gross Motor Function and Risk Factors in Children with Cerebral Palsy：an Epidemiology Study in Chengdu
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摘要: 目的 以人群为基础调查和分析脑瘫儿童粗大运动功能分级和脑瘫高危因素是否存在相关性。方法 收集成都市行政管辖范围内20个区县残联登记在册的2~12岁脑瘫儿童的脑瘫高危因素和基本信息，应用粗大运动功能分级系统（GMFCS）对粗大运动功能进行分级。采用单因素和多因素logistic回归分析方法进行相关性分析。结果 共调查2~12岁脑瘫患儿333例，男女构成比为1.15∶1,平均（6.32±2.74）岁,6-P >0.05）。结论 脑瘫儿童粗大运动功能分级与成都地区脑瘫高危因素之间未见相关性，尚不能用脑瘫高危因素来提示或预测脑瘫患儿粗大运动功能损伤的严重程度。
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关键词:
- 脑性瘫痪 功能 分级 高危因素 流行病学
Abstract: Objective To investigate the correlation between gross motor function and risk factors in children with cerebral palsy (CP). Methods We included the children aged 2-12 years old who were diagnosed with CP and registered in Chengdu Federation of Disabled Persons in 20 districts of Chengdu. Gross motor function was estimated by gross motor function classification system (CMFCS). Risk factors of the CP children were investigated retrospectively. Univariate and multivariate logistic regression analyses were used to analysis the correlation of the CP risk factors and GMFCS grades in the children with CP. Results A total of 333 children were identified with a male to female ratio of 1.15∶1,an average age of （6.32±2.74） years old, and dominated in 6-<12 age group (197 cases,59.16%) and spastic CP (228 cases,68.47%).Thirty risk factors for CP were included, among which the majors were listed as premature delivery （185 cases，55.56%）,low body mass （150 cases，45.05%）,and neonatal hypoxic-ischemic encephalopathy （104 cases，31.23%）.No risk factors of CP were found correlating with GMFCS grades by univariate logistic regression analysis. Stepwise multiple logistic regression analysis showed no risk factors of CP in the regression equation. Conclusion The risk factors of CP can not be used to predict the severity of gross motor function of children with CP. -
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期刊类型引用(8)
1. 王宁宁，刘娅静，尹仁龙，李静静. 脑瘫患儿粗大运动功能分级与高危因素的相关分析及预测模型的构建. 中国妇幼保健. 2022(14): 2596-2600 . 
百度学术
2. 王军，吴猛，周丽杰，郭倩玉，李兵兵，苏春娅，朱登纳. 脑瘫儿童高危因素及其与粗大运动功能的关联分析. 河南预防医学杂志. 2022(11): 801-805+829 . 百度学术
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4. 易爽，余波，庞侯旭. 磷酸肌酸钠联合神经节苷脂治疗新生儿缺氧缺血性脑病的临床疗效. 川北医学院学报. 2021(05): 588-591 . 百度学术
5. 齐倩，段晓娜. 扭动运动对早产儿脑瘫的早期预测效果分析. 中外医疗. 2020(15): 41-43 . 百度学术
6. 马丹，王秋，罗蓉，赵金桂，王芳芳，李娜. 成都地区脑性瘫痪患儿422例伴发小头畸形临床分析. 中国实用儿科杂志. 2019(01): 46-49 . 百度学术
7. 陈海. 康复综合治疗措施对痉挛型脑瘫儿童的运动功能恢复的效果及预后的影响分析. 数理医药学杂志. 2018(07): 1098-1099 . 百度学术
8. 王玎. 脑性瘫痪儿童粗大运动功能分级与孕龄及出生体质量的关系. 中国妇幼保健. 2017(22): 5655-5657 . 百度学术
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