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弱视患者自适应光学系统矫正高阶像差前后视觉行为变化的研究
Visual Performance of Amblyopia before and after Correcting Higher Order Aberrations with Adaptive Optics System
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摘要: 目的 探讨单眼弱视眼通过自适应光学系统矫正高阶像差（higher order aberrations, HOAs）前后视觉行为的变化。 方法 分别测量10名单眼弱视患者通过自适应光学系统矫正弱视眼高阶像差前后的视力(visual acuity, VA)及对比敏感度(contrast sensitivity, CS)阈值，并分析视力和对比敏感度阈值的变化。 结果 弱视眼矫正高阶像差后视力提高（P=0.005）；弱视眼矫正高阶像差后对比敏感度阈值降低(P<0.001),这一进步主要发生于24 cpd的空间频率（spatial frequency, SF）上（P=0.018）。 结论 弱视眼在矫正高阶像差后视觉功能提升，高阶像差的存在对弱视患者高空间频率上对比敏感度功能的下降具有一定的作用。Abstract: Objective To investigate visual performance of monocular amblyopia before and after correcting higher order aberrations (HOAs) with adaptive optics system. Methods Visual acuity (VA) and contrast sensitivity (CS) thresholds of ten monocular amblyopes were measured before and after correcting higher order aberrations with adaptive optics system. The change of them were analyzed. Results A significant improvement of 0.16 times on average (P=0.005) visual acuity of the amblyopic eyes and 0.34 times on average (P<0.001) CS thresholds, mainly improved at 24 cpd were observed. Conclusion The visual performance of amblyopic eyes can be improved after correcting higher order aberrations, and HOAs affect CS at some high spatial frequency.
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