Abstract: Objective To determine the different effects of partial nail avulsion and total nail avulsion with plate replacement with traditional total nail avulsion. Methods Patients were divided into three groups randomly ( n=20): total nail avulsion group (control group), partial nail avulsion group,and total nail avulsion with plate replacement group (nail replacement group). The rating of pain 〔visual analogue scale (VAS) score〕, the wound healing time, the nail growth time ,and the score of satisfaction were analyzed. Results The baseline data of three groups had no significant difference. From 8 h, VAS score of partial nail avulsion group and nail plate replacement group was different with that in control group （ P<0.05）. 48 h after surgery, the pain disappeared totally in partial nail avulsion group, largely in nail replacement group 〔90%（18/20）〕 ,which were both significantly different with that of control group 〔45%(9/20)〕（ P<0.05）. Healing time of three groups was listed as follow: control group＞nail replacement group＞partial nail avulsion group （ P<0.05）. Nail growth time was the longest in control group, the shortest in partial nail avulsion group ( P<0.05, vs. control group), and median in nail replacement group. The score of satisfaction in control group was lower than that in partial avulsion group and nail replacement group（ P<0.05）, of the later two there was no statistic difference. Conclusion By decreasing the defect of nail plate and the injury of nail bed, and by smoothing the pain, partial nail avulsion benefits the wound-healing. Nail plate should be replace to get further benefits.