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不同硬对硬摩擦界面全髋关节置换术后血清钴、铬浓度及临床疗效比较
Clinical Efficacy and Serum Cobalt, Chromium Metal Ion Concentrations after Total Hip Arthroplasty with Three Different Hard-on-Hard Bearings
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摘要: 【摘要】 目的比较全髋关节置换术(total hip arthroplasty,THA)中使用3种不同硬对硬界面后,2年内血清钴、铬金属离子浓度的变化,以及临床疗效有无差异。方法 90例THA患者分为陶瓷对陶瓷(COC)、陶瓷对金属(COM)、金属对金属(MOM)3组,每组30例。术前,术后3、6、12、24月检测血清钴、铬金属离子浓度,进行Harris评分,对患髋进行X片连续性观察和彩超检查。结果 3组术后24月患髋Harris评分达优率均为100%,连续X片显示髋臼假体周围未见透亮线、骨溶解等,彩超均未发现炎性假瘤。术后COM组和MOM组内金属离子浓度迅速升高,至12月时变化趋于平稳,并表现出下降趋势。但MOM组中铬离子浓度则继续上升,24月与12月时比较差异具有统计学意义(上升了0.48μg/L,P=0.021)。术后各时间点COC组相对恒定,MOM组钴、铬金属离子浓度大于COC组和COM组(P<0.05)。结论 3种硬对硬界面术后功能恢复好,无炎性假瘤、骨溶解的发生,都取得了满意的临床效果。COM血清钴、铬金属离子浓度低于MOM,高于COC。 更多还原Abstract: 【Abstract】
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Keywords:
- Total hip arthroplasty /
- Metal ion /
- Ceramic-on-metal /
- Inflammatory pseudotumor
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