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成都市社区老人肌少症患病率及相关因素研究

Prevalence of Sarcopenia and Associated Factors in Community-dwelling Elderly Populations in Chengdu China

  • 摘要: 目的了解成都市社区60岁及以上老人肌少症患病现状,分析影响该人群罹患肌少症的危险因素,为进一步制定肌少症防治策略提供理论依据。方法招募成都市年龄≥60岁社区老人947名,采用生物电阻抗法测量骨骼肌质量,根据亚洲肌少症工作组共识(AWGS)诊断标准诊断肌少症。通过自制量表调查受试者年龄,生活习惯,所患慢性疾病等情况;采用微型营养评估量表(MNA)评估老人营养状况;采用简易智力检查量表(MMSE)评估认知功能;采用老年抑郁量表(GDS-15)评估是否存在抑郁状态。结果成都市≥65岁社区老人肌少症患病率为10.5%,男性为8.4%,女性为12.5%;60~64岁组、65~74岁组及≥75岁组肌少症患病率分别为2.3%,5.6%及19.7%。对肌少症可能相关因素进行logistic回归分析后发现,年龄〔比值比(OR)=1.109,95%可信区间(CI):1.054~1.168〕、吸烟(OR=3.482,95%CI:1.356~8.938)及营养不良风险(OR=5.598,95%CI:2.677~11.709)均与肌少症独立相关。结论成都地区社区60岁及以上老人中,女性肌少症患病率高于男性。年龄、吸烟及营养不良风险可能与罹患肌少症有关。

     

    Abstract: ObjectiveTo determine the prevalence of sarcopenia in community-dwelling elderly populations in Chengdu and its associated risk factors. MethodsA total of 947 community dwelling residents aged ≥60 yr. in Chengdu participated in this study. Their appendicular skeletal muscle mass was measured through bioelectrical impedance analyses. Sarcopenia was defined using the diagnostic algorithm recommended by the Asia Working Group (AWGS) for Sarcopenia. Data in relation to the demographic characteristics,chronic diseases and life style of the participants were obtained through a questionnaire survey,which included the 15-item geriatric depression scale (GDS-15) and the mini nutritional assessment (MNA). ResultsOverall,10.5% of the elderly participants were identified with sarcopenia: 8.4% in men and 12.5% in women. The prevalence of sarcopenia increased with age: 2.3% in the 60-64 yr.,5.6% in the 65-74 yr.,19.7% in the ≥75 yr.. Age 〔odds ratio (OR)=1.109,95% confldence interval (CI):1.054-1.168〕,smoking (OR=3.482,95%CI:1.356-8.938) and Malnorishment (OR=5.598,95%CI:2.677-11.709) are significant predictors of sarcopenia after adjustment for potential confounders. ConclusionApproximately 10% community-dwelling elderly in Chengdu have sarcopenis. Age,smoking,malnutrition are risk factors of sarcopenia.

     

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