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基于倾向得分匹配探讨中国老年人听力损失与认知功能之间的关系

Relationship Between Hearing Loss and Cognitive Function in Elderly Chinese People: A Study Based on Propensity Score Matching

  • 摘要:
    目的 通过倾向得分匹配法,探讨老年人群听力损失与认知功能各维度之间的关系。
    方法 使用中国健康与养老追踪调查(China Health and Retirement Longitudinal Study, CHARLS)2018年的数据,纳入60岁及以上的参与者共7605人。使用无卡钳值、不可替换的1∶1最近邻匹配法进行倾向得分匹配,再用G-computation估计听力损失对认知功能各维度的平均处理效应(average treatment effect, ATE)。
    结果 匹配前,女性3626人(47.68%),听力损失1409人(18.53%),认知障碍3031人(39.86%)。匹配后,听力损失组和听力正常组分别纳入1409例受试者,且两组间人群基本特征分布相似。人群平均处理效应结果显示,听力损失组的认知功能得分均低于正常组,整体认知功能低0.593分〔95%置信区间(confidence intervel, CI): -0.916~ -0.257,P<0.001〕、定向力低0.183分(95%CI:-0.302~-0.055,P=0.004)、即时记忆力低0.150分(95%CI:-0.218~ -0.085, P<0.001),以及语言能力低0.178分(95%CI :-0.303~-0.058,P=0.006)。老年听力损失者的认知障碍患病率比正常者高4.2%(95%CI:0.007~0.077,P=0.020)。
    结论 听力损失影响老年人定向力、记忆力和语言能力,同时也是老年人发生认知障碍的潜在危险因素。

     

    Abstract:
    Objective To explore the relationship between hearing loss and cognitive function in the elderly population through propensity score matching method.
    Methods We analyzed the data of 7605 participants aged 60 and above who were included in the 2018 China Health and Retirement Longitudinal Study (CHARLS). The non-substitutable 1∶1 nearest neighbor matching method without caliper value was used for propensity score matching and G-computation was used to estimate the average treatment effect (ATE) of hearing loss on all dimensions of cognitive function.
    Results Before matching, there were 3626 (47.68%) women, with 1409 (18.53%) of whom suffering from hearing loss and 3031 (39.86%) of whom suffering from cognitive impairment. After matching, 1409 subjects were included in the hearing loss group and 1409, in the normal hearing group, with both groups sharing similar distribution of basic demographic characteristics. The results for the average treatment effect of the population indicated that the cognitive function scores of the hearing loss group were lower than those of the normal hearing group, with the overall cognitive function being 0.593 points lower (95% confidence intervel CI: -0.916--0.257, P<0.001), orientation being 0.183 points lower (95% CI: -0.302--0.055, P=0.004), immediate memory being 0.150 points lower (95% CI: -0.218--0.085, P<0.001), and language skills being 0.178 points lower (95% CI: -0.303--0.058, P=0.006). The prevalence of cognitive impairment of the hearing loss group was 4.2% higher than that of the normal hearing group (95% CI: 0.007-0.077, P=0.020).
    Conclusion Hearing loss adversely affects the orientation, memory, and language skills of the elderly population and forms a potential risk factor for cognitive impairment in the elderly population.

     

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