Impact of Air Pollution and Meteorological Factors on Outpatient Visits for Dermatitis: a Time-series Study

XIE Li; LI An-qi; LI Li

Volume 50 Issue 6

Nov. 2019

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JOURNAL OF SICHUAN UNIVERSITY (MEDICAL SCIENCES) > 2019 > 50(6): 884-890.

XIE Li, LI An-qi, LI Li. Impact of Air Pollution and Meteorological Factors on Outpatient Visits for Dermatitis: a Time-series Study[J]. Journal of Sichuan University (Medical Sciences), 2019, 50(6): 884-890.

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Impact of Air Pollution and Meteorological Factors on Outpatient Visits for Dermatitis: a Time-series Study

Department of Dermatology, West China Hospital, Sichuan University, Chengdu 610041, China

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Corresponding author:
LI Li, E-mail: hxskincos2017@qq.com
Received Date: March 09, 2019
Revised Date: July 14, 2019
Available Online: March 16, 2021
Published Date: November 19, 2019

Abstract

Abstract

Objective To explore the effect of air pollution and meteorological factors on the outpatient visits.
Methods Data of outpatient visits for dermatitis in the West China Hospital of Sichuan University, air pollutants data (SO₂, NO₂, PM₁₀) and meteorological data (barometric pressure, temperature, relative humidity, wind speed)from January 1, 2011 to December 31, 2015 were collected. Distributed lag nonlinear model was used to analyze the influence of air pollution and meteorological factors on the outpatient visits.
Results The daily outpatient amountof dermatitis was positively correlated with PM₁₀ and wind speed, and negatively correlated with SO₂ and temperature. Univariate analysis showed that therelative risk of daily outpatient visits for a 10 μg/m³ increment in SO₂ and NO₂ were 1.003 (95%CI: 1.002-1.004) and 1.002 (95%CI:1.001-1.002) respectively. And the relative risk of daily outpatient visits for a 10% increment in relative humidity was 0.996 (95%CI:0.994-0.997).Multi-pollutant models indicated that air pollutant concentrations were significantly associated with the daily outpatient amount of dermatitis. Distributed lag models showed that the effects of SO₂, NO₂ and PM₁₀ on the daily outpatient amount of dermatitis were mainly observed on the day of exposure. Relative humidity had negative effect on the daily outpatient amount of dermatitis on the day of exposure, in Lag2 days and in Lag4 days.
Conclusion Air pollutants may be a risk factor for dermatitis, and relative humidity can reduce the risk of dermatitis.
- Dermatitis,
- Air pollutants,
- Meteorological factors,
- Distributed lag nonlinear model

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[1]	LI H, CHEN R, MENG X, et al. Short-term exposure to ambient air pollution and coronary heart disease mortality in 8 Chinese cities. Int J Cardiol, 2015, 197:265-270. DOI: 10.1016/j.ijcard.2015.06.050
[2]	LIU Y, XIE S, YU Q, et al. Short-term effects of ambient air pollution on pediatric outpatient visits for respiratory diseases in Yichang city, China. Environ Pollut, 2017, 227:116-124. DOI: 10.1016/j.envpol.2017.04.029
[3]	XIE J, HE M, ZHU W. Acute effects of outdoor air pollution on emergency department visits due to five clinical subtypes of coronary heart diseases in Shanghai, China. J Epidemiol, 2014, 24(6):452-459. DOI: 10.2188/jea.JE20140044
[4]	SINGH S, SHARMA B B, SALVI S, et al. Allergic rhinitis, rhinoconjunctivitis, and eczema:prevalence and associated factors in children. Clin Respir J, 2018, 12(2):547-556. DOI: 10.1111/crj.12561
[5]	GUARNIERI M, BALMES J R. Outdoor air pollution and asthma. Lancet (London, England), 2014, 383(9928):1581-1592. DOI: 10.1016/S0140-6736(14)60617-6
[6]	LEE S Y, CHANG Y S, CHO S H. Allergic diseases and air pollution. Asia Pac Allergy, 2013, 3(3):145-154. DOI: 10.5415/apallergy.2013.3.3.145
[7]	GE E, FAN M, QIU H, et al. Ambient sulfur dioxide levels associated with reduced risk of initial outpatient visits for tuberculosis:a population based time series analysis. Environ Pollut, 2017, 228:408-415. DOI: 10.1016/j.envpol.2017.05.051
[8]	BROWN S, REYNOLDS N J. Atopic and non-atopic eczema. BMJ, 2006, 332(7541):584-588. DOI: 10.1136/bmj.332.7541.584
[9]	ALLAM J P, NOVAK N. The pathophysiology of atopic eczema. Clin Exp Dermatol, 2006, 31(1):89-93. DOI: 10.1159-000083893/
[10]	XU F, YAN S, WU M, et al. Ambient ozone pollution as a risk factor for skin disorders. Br J Dermatol, 2011, 165(1):224-225.
[11]	KIM J, KIM H, LIM D, et al. Effects of indoor air pollutants on atopic dermatitis. Int J Environ Res Public Health, 2016, 13(12): E1220[2019-01-16].https://doi.org/10.3390/ijerph13121220.
[12]	LI Q, YANG Y, CHEN R, et al. Ambient air pollution, meteorological factors and outpatient visits for eczema in Shanghai, China: a time-series analysis. Int J Environ Res Public Health, 2016, 13(11): E1106[2019-01-16]. https://doi.org/10.3390/ijerph13111106.
[13]	GASPARRINI A. Distributed lag linear and non-linear models in r:the package DLNM. J Stat Softw, 2011, 43(8):1-20. http://d.old.wanfangdata.com.cn/OAPaper/oai_doaj-articles_1c10f9127aa6960494de0a921459c07c
[14]	GASPARRINI A, ARMSTRONG B, KENWARD M G. Distributed lag non-linear models. Stat Med, 2010, 29(21):2224-2234. DOI: 10.1002/sim.3940
[15]	BHASKARAN K, GASPARRINI A, HAJAT S, et al. Time series regression studies in environmental epidemiology. Int J Epidemiol, 2013, 42(4):1187-1195. DOI: 10.1093/ije/dyt092
[16]	李永荷, 王旭英, 王巧伟, 等.北京市某医院皮炎患者门诊量与空气污染的相关性研究.中华皮肤科杂志, 2015, 48(12):835-839. DOI: 10.3760/cma.j.issn.0412-4030.2015.12.002
[17]	LI A, FAN L, XIE L, et al. Associations between air pollution, climate factors and outpatient visits for eczema in West China Hospital, Chengdu, South-Western China:a time series analysis. J Eur Acad Dermatol Venereol, 2018, 32(3):486-494. DOI: 10.1111/jdv.14730
[18]	LIU W, CAI J, HUANG C, et al. Associations of gestational and early life exposures to ambient air pollution with childhood atopic eczema in Shanghai, China. Sci Total Environ, 2016, 572:34-42. DOI: 10.1016/j.scitotenv.2016.07.197
[19]	KIM H O, KIM J H, CHO S I, et al. Improvement of atopic dermatitis severity after reducing indoor air pollutants. Ann Dermatol, 2013, 25(3):292-297. DOI: 10.5021/ad.2013.25.3.292
[20]	MAGNANI N D, MURESAN X M, BELMONTE G, et al. Skin damage mechanisms related to airborne particulate matter exposure. Toxicol Sci, 2016, 149(1):227-236. DOI: 10.1093/toxsci/kfv230
[21]	BOWLER R P, CRAPO J D. Oxidative stress in allergic respiratory diseases. J Allergy Clin Immunol, 2002, 110(3):349-356. DOI: 10.1067/mai.2002.126780
[22]	DELL S D, JERRETT M, BECKERMAN B, et al. Presence of other allergic disease modifies the effect of early childhood traffic-related air pollution exposure on asthma prevalence. Environ Int, 2014, 65:83-92. DOI: 10.1016/j.envint.2014.01.002
[23]	LI Q, KANG Z, JIANG S, et al. Effects of ambient fine particles PM_2.5 on human HaCaT cells. Int J Environ Res Public Health, 2017, 14(1): 72[2019-01-16]. https://doi.org/10.3390/ijerph14010072.
[24]	BJERRE R D, BANDIER J, SKOV L, et al. The role of the skin microbiome in atopic dermatitis:a systematic review. Br J Dermatol, 2017, 177(5):1272-1278. DOI: 10.1111/bjd.15390
[25]	HUSS-MARP J, EBERLEIN-KONIG B, BREUER K, et al. Influence of short-term exposure to airborne Der p 1 and volatile organic compounds on skin barrier function and dermal blood flow in patients with atopic eczema and healthy individuals. Clin Exp Allergy, 2006, 36(3):338-345. DOI: 10.1111/j.1365-2222.2006.02448.x
[26]	HALMERBAUER G, FRISCHER T, KOLLER D Y. Monitoring of disease activity by measurement of inflammatory markers in atopic dermatitis in childhood. Allergy, 1997, 52(7):765-769. DOI: 10.1111/j.1398-9995.1997.tb01236.x
[27]	EBERLEIN-KONIG B, PRZYBILLA B, KUHNL P, et al. Influence of airborne nitrogen dioxide or formaldehyde on parameters of skin function and cellular activation in patients with atopic eczema and control subjects. J Allergy Clin Immunol, 1998, 101(1 Pt 1):141-143. http://www.onacademic.com/detail/journal_1000035752967410_1a50.html
[28]	HUANG W H, LIN J H, WENG C H, et al. Environmental NO₂ and CO exposure: ignored factors associated with uremic pruritus in patients undergoing hemodialysis. Sci Rep, 2016, 6: 31168[2019-01-16]. https://doi.org/10.1038/srep31168.
[29]	ONISHI K, OTANI S, YOSHIDA A, et al. Adverse health effects of Asian dust particles and heavy metals in Japan. Asia Pac J Public Health, 2015, 27(2):NP1719- NP1726. DOI: 10.1177/1010539511428667
[30]	CAKMAK S, DALES R E, COATES F. Does air pollution increase the effect of aeroallergens on hospitalization for asthma? J Allergy Clin Immunol, 2012, 129(1):228-231.
[31]	SILVERBERG J I, HANIFIN J, SIMPSON E L. Climatic factors are associated with childhood eczema prevalence in the United States. J Invest Dermatol, 2013, 133(7):1752-1759. DOI: 10.1038/jid.2013.19
[32]	GOAD N, GAWKRODGER D J. Ambient humidity and the skin:the impact of air humidity in healthy and diseased states. J Eur Acad Dermatol Venereol, 2016, 30(8):1285-1294. DOI: 10.1111/jdv.13707
[33]	VAN ZUUREN E J, FEDOROWICZ Z, CHRISTENSEN R, et al. Emollients and moisturisers for eczema. Cochrane Database Syst Rev, 2017, 2: CD012119[2019-01-16]. https://doi.org/10.1002/14651858.CD012119.2.pub2.
[34]	KATHURIA P, SILVERBERG J I. Association of pollution and climate with atopic eczema in US children. Pediatr Allergy Immunol, 2016, 27(5):478-485. DOI: 10.1111/pai.12543
[35]	LEE Y L, SU H J, SHEU H M, et al. Traffic-related air pollution, climate, and prevalence of eczema in Taiwanese school children. J Invest Dermatol, 2008, 128(10):2412-2420. DOI: 10.1038/jid.2008.110

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Impact of Air Pollution and Meteorological Factors on Outpatient Visits for Dermatitis: a Time-series Study

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