The Clinical Evaluation of Prosthetic Valve in Patients with Dysfunction Valve Endocarditis

ObjectiveTo evaluate the outcomes of valve replacement of endocarditis using bioprothetic and mechanical valves. Methods This study comprised 52 patients 〔mean age （47±18) yr., mean follow-up time (6.2±3.8) years〕 underwent valve endocarditis with bioprotheses, The control group were matched (3∶1) with 156 patients of endocarditis underwent mechanical valves replacement using the following variables: age±5 yr., body mass index (BMI)±20%, time of operation±1 year, replacement position and sex ratio. And evaluate the effects of using bioprothetic and mechanical valves on perioperative and long-term outcomes of valve replacement of endocarditis. Results The perioperative mortality of the patients receiving bioprothetic and mechanical valves were 17.3%±2.2% and 19.9%±1.8%, respectively, which was independent of valve type (P=0.27). Long-term survival were 56.1%±5.2% and 61.2%±8.1%, respectively (P=0.58). Meanwhile, long-term complication-free survival were 75.0%±3.2% and 82.3%±4.4%, respectively (P=0.29). For the patients younger than or equal to 60 yr., long-term reoperation rates for bioprothetic and mechanical valves were 41.4%±7.2% and 30.5%±5.4% (P=0.02). For the patients older than 60 yr., however, reoperation rates were 24.1%±8.5% and 14.7%±5.7% (P=0.36). Conclusion Perioperative mortality and long-term survival are independent to valve types in patients with endocarditis. Mechanical valve shows potential advantage compared with bioprothetic valve in the patients younger than 60-year-old.