Application of Polysomnography in Common Neurodegenerative Diseases

CHEN Zhangyue; LI Taomei; TANG Xiangdong

doi:10.12182/20230960304

Volume 54 Issue 5

Oct. 2023

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JOURNAL OF SICHUAN UNIVERSITY (MEDICAL SCIENCES) > 2023 > 54(5): 1058-1064. > DOI: 10.12182/20230960304

CHEN Zhangyue, LI Taomei, TANG Xiangdong. Application of Polysomnography in Common Neurodegenerative Diseases[J]. Journal of Sichuan University (Medical Sciences), 2023, 54(5): 1058-1064. DOI: 10.12182/20230960304

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Application of Polysomnography in Common Neurodegenerative Diseases

Sleep Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, China

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Corresponding author:
TANG Xiangdong, E-mail: 2372564613@qq.com
Received Date: December 16, 2022
Revised Date: September 08, 2023
Available Online: October 12, 2023
Published Date: October 12, 2023

Abstract

Abstract

At present, the etiology and pathogenesis of most neurodegenerative diseases are still not fully understood, which poses challenges for the prevention, diagnosis, and treatment of these diseases. Sleep disorders are one of the common chief complaints of neurodegenerative diseases. When patients suffer from comorbid sleep disorder and neurodegenerative diseases, the severity of their condition increases, the quality of their life drops further, and the difficulty of treatment increases. A large number of studies have been conducted to monitor the sleep of patients with neurodegenerative diseases, and it has been found that there are significant changes in their polysomnography (PSG) results compared to those of healthy control populations. In addition, there are also significant differences between the PSG findings of patients with different neurodegenerative diseases and the differences are closely associated with the pathogenesis and development of the disease. Herein, we discussed the characteristics of the sleep structure of patients with Parkinson's disease, Alzheimer's disease, Huntington's disease, and dementia with Lewy bodies and provided a brief review of the sleep disorders and the PSG characteristics of these patients. The paper will help improve the understanding of the pathogenesis and pathological changes of neurodegenerative diseases, clarify the relationship between sleep disorders and these diseases, improve clinicians' further understanding of these diseases, and provide a basis for future research.
- Neurodegenerative diseases,
- Polysomnography,
- Sleep disorder

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