Welcome to JOURNAL OF SICHUAN UNIVERSITY (MEDICAL SCIENCES)
LIN Wei-min, YUAN Quan. Latest Research Findings on Immune Microenvironment Regulation in Jawbone-Related Diseases[J]. Journal of Sichuan University (Medical Sciences), 2022, 53(3): 528-531. DOI: 10.12182/20220560502
Citation: LIN Wei-min, YUAN Quan. Latest Research Findings on Immune Microenvironment Regulation in Jawbone-Related Diseases[J]. Journal of Sichuan University (Medical Sciences), 2022, 53(3): 528-531. DOI: 10.12182/20220560502

Latest Research Findings on Immune Microenvironment Regulation in Jawbone-Related Diseases

  • Among the bones of the whole body, the jawbone is considered the region where remodeling takes place the most actively. In this region, the homeostasis of the bones is maintained by the balanced activities of osteoblasts and osteoclasts. The bone immune microenvironment can simultaneously regulate osteoblasts and osteoclasts. Compared with other bones, the jawbone is more susceptible to pathogens because it is exposed to the bacteria in the oral environment. In the case of inflammatory pathology, an over-activated immune system stimulates the activation of osteoclasts and inhibits osteoblasts. In this review, we summarized the different characteristics of the bone immune microenvironment of the jawbone compared with other bones, and the role of immune microenvironment regulation in common jawbone diseases. The development of corresponding therapeutic strategies for jawbone immune regulation targets may be helpful for the treatment of jawbone inflammatory diseases.
  • loading

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return