Welcome to JOURNAL OF SICHUAN UNIVERSITY (MEDICAL SCIENCES)

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Research Advances on Mechanisms and Interventions of DNA Methylation-Regulated Aging-Related Imbalance in Bone Metabolism
He Tailin, Li Jie, Mei Yifang, Xiao Guozhi
2026, 57(4): 905-914. DOI: 10.12182/20260760301
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Systemic Reprogramming of Cellular Senescence: Coordinated Regulation of Metabolism, Epigenetics, and Proteostasis
Zheng Yulin, Liu Qian, Wang Ruihong, Sun Chongkui
2026, 57(4): 915-924. DOI: 10.12182/20260760105
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Oral-Systemic Antiaging Mechanisms and Intervention Strategies Guided by Traditional Chinese Medicine Principle of Preventive Treatment of Disease
Ai Huangping, Li Chuncai, Jin Zhao, Zuo Yuling
2026, 57(4): 925-932. DOI: 10.12182/20260760201
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Oral Aging: Age-Related Changes and Their Association With Systemic Aging
Gong Yuanjia, Zhou Chenchen, Fan Yi
2026, 57(4): 933-940. DOI: 10.12182/20260760106
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Age-Related Changes in the Oral Microbiota
Zhou Jingzhi, Ye Xingchen, Zou Jing, Zou Ling, Cheng Lei, Zhu Zhuoli, Liao Ga, Zhou Xuedong, Ren Biao
2026, 57(4): 941-952. DOI: 10.12182/20260760601
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Research Advances on the Role of the Oral Microbiota in Age-Related Homeostatic Dysregulation and Systemic Diseases
HE Zhuojia, LI Dongliang, PENG Xian
2026, 57(4): 953-958. DOI: 10.12182/20260760602
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Age-Related Changes in Occlusion and the Clinical Management and Prevention Strategies
Wang Meiqing
2026, 57(4): 959-965. DOI: 10.12182/20260760202
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Interdisciplinary Research on Artificial Intelligence and Longevity Medicine: Global Landscape, Collaboration Networks, and Frontier Trends (2010–2025)
Huang Xinyan, Tan Jianshu, Cao Shuqin, Di Longkang, Kang Lunwei, Zhu Zhuoli, Liao Ga
2026, 57(4): 966-973. DOI: 10.12182/20260760501
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Shashen Maidong Decoction Improves Pulmonary Function in Aged Mice With Chronic Obstructive Pulmonary Disease by Inhibiting cGAS-STING-NF-κB-Mediated Inflammaging
Kuang Xiangnan, Liu Xingran, Zhao Xinyao, Chen Xuexiao, Liu Shiqiao
2026, 57(4): 974-984. DOI: 10.12182/20260760107
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Effect of Long-term Exposure to PM2.5 and Its Chemical Components on Frailty Incidence in Middle-aged and Older Adults in China: A Prospective Cohort Study
Chen Kun, Liu Qian, Wu Chenchen, Yang Lihua, Lin Xiaojun
2026, 57(4): 985-992. DOI: 10.12182/20260760103
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Relationship Between Pain and Depressive Symptoms in Middle-aged and Older Chinese Adults: A Cross-Lagged Longitudinal Analysis
Xia Honghong, Wangmu, Zhang Hongxia, Fu Ming, Wan Yang, Qiu Peiyuan
2026, 57(4): 993-999. DOI: 10.12182/20260760603
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Effects of Exercise Training Combined With β-Hydroxy-β-Methylbutyrate Supplementation on Physical Function in Older Adults With Frailty
Jiang Yanxing, Yang Haolun, Yin Ziwen, Zhang Liming, Wang Renjie
2026, 57(4): 1000-1008. DOI: 10.12182/20260760110
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Effects of Blood Flow Restriction Training on Muscle Strength and Physical Function in Older Adults With Sarcopenia
Liang Yuxiang, Wu Yuqi, Chun Xueli, Wang Ruili, Jiang Jiaojiao
2026, 57(4): 1009-1014. DOI: 10.12182/20260760203
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Tongdu Zhiyu Acupuncture Improves Post-Stroke Depression by Upregulating miR-223-3p and Inhibiting NLRP3 Inflammasome: A Clinical Study
Zhang Jingbo, Hu Huixing, Liang Fajun, Yin Miaomiao, Wang Baoguo, Zhang Xianbao, Zheng Zhijun, Wang Zhen
2026, 57(4): 1015-1021. DOI: 10.12182/20260760604
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Metformin Inhibits Prostate Cancer Progression via Regulation of the AKT/mTOR Signaling Pathway
Zhang Zhengkun, Quan Zhiyou, Dai Panpan, Xu Keyi, Yin Zhaoru, Chen Dan, Geng Ruiman, Ji Xuxu, Wang Dingxue, Chen Shu, Chen Lihong, Liu Ji
2026, 57(4): 1022-1031. DOI: 10.12182/20260760204
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CAMK2a Regulates Paclitaxel Resistance in Oral Squamous Cell Carcinoma Cells by Activating the ERK Signaling Pathway
Wang Junfeng, Chen Hongli, Chen Jiao, Feng Yun, Yuan Yao, Zhang Ping
2026, 57(4): 1032-1041. DOI: 10.12182/20260760402
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Molecular Mechanism of microRNA-429 Targeting HMOX1 to Regulate Invasion, Migration, and Ferroptosis in Lung Adenocarcinoma Cells
Gao Xinyu, Gong Xiuying, Hou Shunfu, Zhang Zhihan, Li Hongli, Wang Xuejing
2026, 57(4): 1042-1051. DOI: 10.12182/20260760605
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Role and Potential Mechanisms of Peroxisome Proliferator-Activated Receptor α in Ultraviolet B Radiation-Induced Skin Damage
Jiang Fengdi, Liu Yifan, Wang Mingyu, Xie Xiaotao, Maheliya Adili, Du Mengjie, Wang Jiajia, Xiong Hai, Zhang Shuyu
2026, 57(4): 1052-1061. DOI: 10.12182/20260760403
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Anti-inflammatory Mechanisms of Human Resistin Through Activation of Peroxisome Proliferator-Activated Receptor γ
Shi Bowen, Han Bin, Liu Yulin, Liu Renping
2026, 57(4): 1062-1072. DOI: 10.12182/20260760502
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Effect of Cancer Antigen-125 Elimination Rate Constant K and BRCA Mutation Status on the Prognosis of Interval Debulking Surgery in Advanced High-Grade Serous Ovarian Cancer
Li Yuebo, Li Mengru, Zhang Xiuyun, Xu Hanjie, Li Jie, Liu Hanyuan, Peng Cheng
2026, 57(4): 1073-1079. DOI: 10.12182/20260760404
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Evaluation of the Effects of Body Scan Mindfulness Training in Patients With Burning Mouth Syndrome
He Jing, Xiao Ning, Hu Mingjia, Li Jia, Liu Fan
2026, 57(4): 1080-1085. DOI: 10.12182/20260760503
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Neuropsychological Risk Factors for Chronic Postoperative Pain Following Abdominal Surgery
Huang Yanjun, Yu Weimin, Ning Jie, Wang Shuyuan, Li Xiaohuan, Sun Lipeng
2026, 57(4): 1086-1092. DOI: 10.12182/20260760104
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Efficacy and Long-term Prognosis of Flumatinib in the Treatment of Chronic Myelocytic Leukemia
Xia Liang, Bao Jing, Huang Zhenqi, Wu Wei, Chen Xiaowen
2026, 57(4): 1093-1097. DOI: 10.12182/20260760108
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Influencing Factors for Secondary Fungal Infections in Systemic Lupus Erythematosus
Li Chunlin, Fan Qiuyu, Xiao Yu, Song Ting, Zong Ziye, Yang Wei
2026, 57(4): 1098-1106. DOI: 10.12182/20260760205
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Prognostic Outcomes and Influencing Factors in Children With Severe Pneumonia Complicated by Mycoplasma Infection
Zhou Chen, Yi Yan, Tan Yun, Jiang Xueping, Ming Yangcan
2026, 57(4): 1107-1113. DOI: 10.12182/20260760206
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Risk Factors for Idiopathic Membranous Nephropathy Complicated by Acute Kidney Injury
Cai Jiaying, Chen Yaling, Lai Suren, Shen Shizhong
2026, 57(4): 1114-1120. DOI: 10.12182/20260760207
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Independent Risk Factors for Venous Thromboembolism After Gynecological Surgery and the Predictive Value of Postoperative D-Dimer
Fang Fei, Sun Yuchen, Sun Tianyi, Lü Chuhan, Miao Yali, Zhao Zhiwei
2026, 57(4): 1121-1129. DOI: 10.12182/20260760606
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Value of Multivariate Computed Tomography Angiography for Predicting Major Adverse Cardiac Events in Patients With Coronary Artery Heart Disease
Tu Bo, Xiao Weiliang, Pan Zhihua, Liu Jia, Xiao Ke, Li Hongcheng, Li Jian, Liu Dongmei, Zhao Dechun, Xie Hongying
2026, 57(4): 1130-1136. DOI: 10.12182/20260760102
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Construction and Validation of a Risk Prediction Model for Catheter Blockage in Patients With Implantable Venous Access Ports
Zhang Shuang, Han Suli, Zhao Ningjun
2026, 57(4): 1137-1144. DOI: 10.12182/20260760607
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Development and Validation of a Nomogram Prediction Model for Pulmonary Infection in Cerebral Infarction Patients During the Recovery Phase After Acupuncture Treatment
Hu Jin, Chu Haoran, Wang Ying, Li Chenglong
2026, 57(4): 1145-1152. DOI: 10.12182/20260760504
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Development of a Risk Prediction Model for Moderate-to-Severe Complications Associated With Peripheral Intravenous Catheters in Older Patients
Chen Xiao, Guo Yuchen, Liang Zhimin, Li Lingli
2026, 57(4): 1153-1159. DOI: 10.12182/20260760109
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Characteristics and Drug Resistance Analysis of Urogenital Mycoplasma Infections in Patient Specimens From Non-Gynecologic Departments
Zhou Dan, Yuan Yu, Liu Ya, Xiao Yuling
2026, 57(4): 1160-1164. DOI: 10.12182/20260760208
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Prevalence of Refractive and Corneal Astigmatism in Children Aged 3-14 Years
Zhao Yuxuan, Yang Bi, Luo Hui, Li Rong, Chen Rui, Liu Longqian, Yan Naihong
2026, 57(4): 1165-1170. DOI: 10.12182/20260760209
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Association Between Marital/Partner Relationship Quality and Accumulation Rate of Multiple Chronic Conditions in Middle-Aged and Older Adults: An Analysis Based on Data From English Longitudinal Study of Ageing
Chen Rui, Xiang Yi, Xin Minglun, Xiao Xiong
2026, 57(4): 1171-1178. DOI: 10.12182/20260760608
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In Vitro Biosafety Evaluation of Biodegradable Fluorinated Polyurethane Micelles
Wang Chaoyang, Sun Lu, Deng Ya, Li Jiehua, Tan Hong, Xu Jianguo, Liang Ruichao
2026, 57(4): 1179-1186. DOI: 10.12182/20260760401
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Construction of a Multi-Factor Quantitative Scoring Model for Chromosome Karyotype Analysis
Lai Yi, Su Qian, Wang Hao, Wu Weihang, He Guolin, Li Tao
2026, 57(4): 1187-1194. DOI: 10.12182/20260760505
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Structured Annotation and Information Extraction of Epilepsy Clinical Texts
Jin Ling, He Mengqiao, Basangsijia, Feng Duanyu, Lei Wenqiang, Chen Lei
2026, 57(4): 1195-1203. DOI: 10.12182/20260760210
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Applications and Challenges of Deep Learning in Human Genome Research
Li Yucong, Tu Kailing, Xie Dan
2026, 57(4): 1204-1211. DOI: 10.12182/20260760302
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Research Progress on the Application of CRISPR/Cas System in Rapid Testing of Drug-Resistant Bacteria in Clinical Practice
Song Zhen, Li Hui, Zhao Yanan, Li Min
2026, 57(4): 1212-1220. DOI: 10.12182/20261360301
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Clinical Challenges in the Diagnosis and Management of Fetal Esophageal Atresia: From Prenatal Diagnosis and Surgical Intervention to Prognostic Management
Sun Mengmeng, Zhou Fan, Wang Xiaodong, Wan Li, Yu Haiyan
2026, 57(4): 1221-1227. DOI: 10.12182/20260760111
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Risk Identification and Standardized Prevention and Control Strategies for Outsourced Laboratory Testing in Healthcare Institutions
Ran Longyao, Zeng Wenbo, Liu Danni, Guo Xiaowei
2026, 57(4): 1228-1234. DOI: 10.12182/20260760506
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