Welcome to JOURNAL OF SICHUAN UNIVERSITY (MEDICAL SCIENCES)

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Future-Oriented High-Quality Development of Integrated Traditional Chinese and Western Medicine
CHEN Xiangmei, WANG Conghui, ZHANG Qinxiu, LI Yan, TANG Yong
2025, 56(1): 1-4. DOI: 10.12182/20250160401
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Interpretation of the Guidelines for Integrated Traditional Chinese and Western Medicine Diagnosis and Treatment of Liver Cirrhosis
LYU Wenliang, CAO Zhengmin, YE Yong’an, XING Lianjun
2025, 56(1): 5-9. DOI: 10.12182/20250160201
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Role of Traditional Chinese Medicine in Pathogen-Induced Metabolic Reprogramming and Immune Suppression
DANG Yixiong, SUN Xin, JIANG Jingwen
2025, 56(1): 10-18. DOI: 10.12182/20250160501
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Research Progress in the Mechanisms of Acupuncture in Regulating DNA Methylation
GAO Sujin, PAN Xinru, LIU Baitong, LUO Ling, XIONG Xiaoyi, YU Shuguang
2025, 56(1): 19-25. DOI: 10.12182/20250160101
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Mechanisms by Which Paraventricular Hypothalamic Nucleus Participates in the Acupuncture Treatment of Diseases
BAI Ziyou, ZHANG Chaoran, RAO Yiqing, LIN Qishun, YU Lingling, LIU Jiabao, JING Xianghong, LI Man
2025, 56(1): 26-34. DOI: 10.12182/20250160202
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Berberine Alleviates Chronic Retinal Light Damage in Mice: A Study of the Role of P2X7R and the Mechanisms Involved
DAI Leshu, YE Shanshan, SONG Zixuan, SONG Jiantao
2025, 56(1): 35-40. DOI: 10.12182/20250160505
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Wogonoside Attenuates Hypertension-Induced Renal Injury Through Modulation of the MAPK Signaling Pathway: A Mechanism Study
GUO Zhi, XIE Yi, LIU Hongshu, XIAO Jundan, CHEN Rongji, WU Meizhu, PENG Jun, SHEN Aling
2025, 56(1): 41-50. DOI: 10.12182/20250160103
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Biejiajian Pill Regulates Ferroptosis in Hepatocellular Carcinoma Cells via p62/Keap1/NRF2 Signaling Pathway: A Mechanism Study
CHEN Weiguang, HE Chunyu, WEN Bin, SUN Haitao, YANG Xuemei, CHEN Weicong, LIU Yang, ZHONG Binglian, HE Songqi
2025, 56(1): 51-58. DOI: 10.12182/20250160502
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Characteristics of Aurora Kinase A-Mediated Tumor Microenvironment in Colorectal Cancer and Mining of Active Compounds From Chinese Herbs
LI Mengyao, HUA Dongming, WANG Zhiyan, LIU Zhiyi, GONG Hangjun, SUN Yunchuan, HU Xueqing, WANG Yan
2025, 56(1): 59-67. DOI: 10.12182/20250160104
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Mechanisms of Wandai Decoction in Improving Vaginal Flora of Vulvovaginal Candidiasis of the Spleen Deficiency and Excessive Dampness Type: A Study Based on Metagenomics and Metabolomics
HAN Yue, SHEN Su, FU Jie, REN Qingling
2025, 56(1): 68-73. DOI: 10.12182/20250160110
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Molecular Mechanisms of Huangjing Zanyu Capsule in Treating Oligoasthenospermia: A Study Based on AMPK-Mediated Mitophagy
GAO Yuan, GUO Yiyang, WU Mohan, ZHENG Yanfei
2025, 56(1): 74-82. DOI: 10.12182/20250160504
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Lupeol Alleviates Chondrocytes Senescence in Osteoarthritis by Regulating Autophagy via the Sirtuin 3/Mechanistic Target of Rapamycin Kinase Pathway
MA Yunfeng, CAO Yujing, HAN Xiaofei
2025, 56(1): 83-93. DOI: 10.12182/20250160503
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Effects and Efficacy of Wenyang Huayin Yangxin Prescription on the Traditional Chinese Medicine Syndromes of Patients With Chronic Heart Failure Combined With Diuretic Resistance
WU Jiali, XIAO Dan, ZHAN Tao, YUAN Yi, ZHAN Yun, LIU Hong
2025, 56(1): 94-101. DOI: 10.12182/20250160109
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Gandou Bushen Decoction Ameliorates Cognitive Impairment in Wilson Disease Model TX Mice by Regulating Melatonin Synthesis via the SIRT3/FOXO3α Pathway
WANG Luyao, WU Limin, WANG Tingting, FANG Xinru, JIANG Zhenzhen, YUE Yike, ZHAO Dan, LIU Qianzhuo, HAN Hui
2025, 56(1): 102-111. DOI: 10.12182/20250160602
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Targets and Molecular Mechanisms of Salidroside in Improving High-Altitude Cognitive Function
SUN Yuemei, QIN Ningning, JI Qian, WANG Yanling, QIU Fangfang, SUN Jielong, WANG Rong
2025, 56(1): 112-119. DOI: 10.12182/20250160603
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Mechanisms of the Anti-Fibrotic Effect of Ginsenoside Rh1 on Hepatic Fibrosis
CHEN Xuan, YANG Sai, NAN Bo, MA Jisheng, WANG Yanfang
2025, 56(1): 120-128. DOI: 10.12182/20250160203
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Moxibustion Inhibits Postmenopausal Bone Loss by Regulating the Metabolism of Gut Microbiota-Related Serotonin
HUANG Xianhao, Camilo Alberto Pinzon Galvis, XU Huimin, LU Lingyun, YANG Han, LI Ning, WEN Qian
2025, 56(1): 129-136. DOI: 10.12182/20250160604
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Optimal Timing of Moxibustion Intervention for Anti-inflammatory and Analgesic Effects Based on a Chronic Inflammatory Pain Model
ZHOU Ruizhu, HE Liuxuan, Hou Shuai, YANG Sha, YIN Haiyan, YU Shuguang
2025, 56(1): 137-142. DOI: 10.12182/20250160605
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Legal Risk Assessment and Prevention in Artificial Intelligence-Assisted Health Care
YANG Jinming, WANG Na, HU Yexun, ZHANG Wei
2025, 56(1): 143-148. DOI: 10.12182/20250160301
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Different Types of Obesity Play a Modifying Role in the Association Between Physical Activity and Metabolic Dysfunction-Associated Fatty Liver Disease
CHANG Yang, LI Jiawei, WU Gonghua, ZHANG Juying, GUO Bing, ZHAO Xing
2025, 56(1): 149-155. DOI: 10.12182/20250160108
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Effects of Inhibiting the NKCC1/AQP4 Pathway on Neurological Injury Improvement in a Rat Model of High-Altitude Cerebral Edema
GENG Huali, LI Baichuan, SONG Xu, XIA Yilin, ZHOU Xiangyang, GAO Jing, CHEN Lei
2025, 56(1): 156-165. DOI: 10.12182/20250160204
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Benchmarking China's Top-Tier Medical Institutions Against Global Standards: A Quantitative Analysis of the Gap Using Internationally Recognized Metrics
YANG Gui, CUI Yajuan, DAI Rui, ZHANG Qiuqiu, LUO Wenqi
2025, 56(1): 166-174. DOI: 10.12182/20250160302
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Nafamostat Mesylate Alleviates Renal Ischemia-Reperfusion Injury in a Rat Model Through HMGB1 Modulation: An Omics Analysis -Based Study of the Protective Effect and the Mechanisms Involved
WU Yuxuan, LI Hongqian, LIU Linfeng, WANG Yu, CHEN Bo, LIU Jiang, QIN Jianhua, OU Santao, WU Weihua
2025, 56(1): 175-182. DOI: 10.12182/20250160506
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Predicting Intensive Care Unit Mortality in Patients With Heart Failure Combined With Acute Kidney Injury Using an Interpretable Machine Learning Model: A Retrospective Cohort Study
LUO Xinyao, WAN Dingyuan, WANG Ke, LI Yupei, LIAO Ruoxi, SU Baihai
2025, 56(1): 183-190. DOI: 10.12182/20250160507
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Prophyromonas gingivalis Promotes the Formation of Immunosuppressive Microenvironment in Oral Squamous Cell Carcinoma by CCR6+ Regulatory T Cells: A Study of the Mechanisms Invovled
XU Liming, TIAN Xiao, WANG Jie, ZHANG Yibo, NAIJIBAI· MOMIN, LING Bin
2025, 56(1): 191-197. DOI: 10.12182/20250160105
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Preparation of Trop2-Targeted CAR-T Cells Based on Nanobodies and Their Antitumor Effects Against Non-Small Cell Lung Cancer
WEN Jing, LI Xin
2025, 56(1): 198-205. DOI: 10.12182/20250160107
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Effects of Vitamin B12 on Behaviors, Brain Monoamine Neurotransmitters, and Brain-Derived Neurotrophic Factor in Depressive Rats
CHEN Jing, LIU Jinchun, ZHANG Pengjie, ZHANG Shenqi
2025, 56(1): 206-214. DOI: 10.12182/20250160608
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Characteristics of Flow and Heat Transfer in the Upper Respiratory Tract of Humans Under Nasal Obstructive Conditions
PAN Hui, XIE Jun, GAO Weiye, CHEN Wei
2025, 56(1): 215-221. DOI: 10.12182/20250160102
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Mechanisms of 6-Hydroxygen Genistein in the Treatment of Pulmonary Injury in High-Altitude Hypoxic Mice
MA Chuan, WANG Xiaojuan, YANG Chenyu, ZHANG Shuyu, YANG Baole, JING Linlin, MA Huiping
2025, 56(1): 222-229. DOI: 10.12182/20250160205
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Longitudinal Transitions of Fall States Based on a Multi-State Markov Model and Their Associated Risk Factors
KOU Wenkai, YE Suni, CHEN Xuerui, HUANG Jing, SHI Sailong, QIU Peiyuan
2025, 56(1): 230-238. DOI: 10.12182/20250160510
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Quantitative Risk Assessment of Listeria monocytogenes in Prepackaged, Non-Vacuum Sealed, Refrigerated Ready-to-Eat Cooked Meat Products in Chengdu
LIU Xiao, SUN Honghu, WANG Xiang, LIU Lisha, GUO Ting, SUN Yue, WANG Jun, BAI Li
2025, 56(1): 239-246. DOI: 10.12182/20250160303
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Value of Blood Uric Acid/Creatinine Ratio and Osteoporosis Self-Assessment Tool for Asians for Predicting Osteoporosis in Middle-Aged, Older, and Elderly Adult Tibetan Populations in Xizang
DING Kangzhi, WANG Peng, ZHANG Jing, ZHANG Yufei, XIONG Hai
2025, 56(1): 247-253. DOI: 10.12182/20250160508
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Investigation and Analysis of Deacclimatization in Tibetan College Students Upon First Visit to Low-Altitude Regions
ZHANG Weihua, HAN Kezhen, SHAO Li, YANG Chao, ZHAO Kexin, JIANG Zhao
2025, 56(1): 254-261. DOI: 10.12182/20250160509
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Establishment and Evaluation of a Nucleic Acid Amplification Test for Spectinomycin-Resistant Neisseria gonorrhoeae
YANG Guiqin, LI Menghuan, WANG Youwei, YONG Gang, WANG Hongren, BIE Mingjiang
2025, 56(1): 262-267. DOI: 10.12182/20250160402
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Preparation of a Microneedle Patch Loaded With Sodium Houttuyfonate Combined With Erythromycin and Its Antiacne Effects
WU Tingting, CHEN Qingru, LU Xuemei
2025, 56(1): 268-276. DOI: 10.12182/20250160206
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Clinical Manifestations of Early-Onset Capillary Leak Syndrome in Patients With Multiple Organ Failure Due to Severe Acute Pancreatitis
WU Xueying, LI Lan, SHI Jiahua, LI Jie, LI Ziyu, LIN Ziqi, LIU Tingting, JIN Tao, XIA Qing
2025, 56(1): 277-283. DOI: 10.12182/20250160609
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Outcomes of Endoscopic Treatment of Esophagogastric Variceal Bleeding and Construction and Validation of a 1-Year Rebleeding Risk Prediction Model
YANG Jianbo, HUANG Xiaomei, HE Yuanjing, ZHANG Lili, LUO Yujun
2025, 56(1): 284-290. DOI: 10.12182/20250160106
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