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闫沛静, 詹凤羽, 侯利莎等. 病灶部位与缺血性脑卒中幸存者生命质量变化趋势关系的研究[J]. 四川大学学报(医学版), 2015, 46(6): 860-865.
引用本文: 闫沛静, 詹凤羽, 侯利莎等. 病灶部位与缺血性脑卒中幸存者生命质量变化趋势关系的研究[J]. 四川大学学报(医学版), 2015, 46(6): 860-865.
YAN Pei-jing, ZHAN Feng-yu, HOU Li-sha. et al. Lesion Locations and Quality of Life in Patients with Ischemic Stroke[J]. Journal of Sichuan University (Medical Sciences), 2015, 46(6): 860-865.
Citation: YAN Pei-jing, ZHAN Feng-yu, HOU Li-sha. et al. Lesion Locations and Quality of Life in Patients with Ischemic Stroke[J]. Journal of Sichuan University (Medical Sciences), 2015, 46(6): 860-865.

病灶部位与缺血性脑卒中幸存者生命质量变化趋势关系的研究

Lesion Locations and Quality of Life in Patients with Ischemic Stroke

  • 摘要: 目的 探讨缺血性脑卒中幸存者病灶部位与生命质量变化趋势的关系。方法 采用欧洲五维健康量表(EQ-5D)定期观测456例初发缺血性脑卒中幸存者2年期间的生命质量。采用CT、MRI结合临床特征确定病灶部位;并采用多水平模型分析病灶部位与生命质量变化趋势的关系。结果 研究对象中约3/5幸存者为前循环缺血(ACI)病灶,ACI中约1/2幸存者的病灶位于皮质下;左、右半球病变者的比例为1∶1。多水平模型分析结果提示病灶据大脑侧别分类,仅右侧大脑半球病变者与非大脑病变者生命质量的变化趋势不一致( P<0.001);而根据受累的脑血管系统及脑部解剖结构分类,提示前循环皮质及以下均有病变者与同类别其他组间生命质量的变化趋势均不一致( P<0.044)。结论 病灶部位对脑卒中幸存者生命质量的变化趋势有影响。建议今后研究者尝试根据受累的脑血管系统和脑部解剖结构对病灶进行更详细的分类,并结合病灶大小,进一步探索病灶部位与生命质量的关系。

     

    Abstract: Objective To determine the prevalence of high risk sex behaviors and associated factors in 18-34 years old men in Chengdu. Methods An anonymous questionnaire survey was conducted in 18-34 years old men selected by multi-stage random sampling in Chengdu. Data of 1536 respondents who reported having sex contacts were analyzed. Results 23.6% of respondents had multiple sex partners in the past 12 months; 11.8% were involved commercial sex; 9.0% had group sex; 4.7% had anal sex; 15.6% had never used a condom; 37.7% had sex under the influence of alcohol or drugs. Logistic regression analysis revealed that marital status 〔married, standardized partial regression coefficient (B)=-0.086, P<0.05〕, level of education (bachelor or above, B=-0.063, P<0.05), frequency of exposure to pornography (B=0.058, P<0.05), childhood sexual abuse (B=0.042, P<0.05), first sexual intercourse at an earlier age (B=0.162, P<0.05), frequency of sex under the influence of alcohol or drugs (B=0.054, P<0.05) were significant predictors of having multiple sexual partners. Sexual orientation, age, smoking, alcohol abuse, drug use, anxiety, depression, childhood physical abuse did not appear to be significant factors associated with having multiple sexual partners. Conclusion Having multiple sexual partners is the main high risk sex behavior of young men in Chengdu. Childhood sexual abuse and early start of sexual intercourse are the major predictors of having multiple sexual partners.

     

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