Abstract: The innovative development of integrating digital technology with education has created a new framework and ecosystem for stomatology education. Taking the innovative ecological construction of experimental teaching at West China School of Stomatology, Sichuan University as a representative case, we systematically explored the innovative pathways and practical paradigms for experimental teaching in stomatology empowered by digital intelligence across multiple dimensions, including knowledge acquisition, clinical competency development, and evaluation of experimental teaching. A 4-wheel–driven stomatology experimental teaching system comprising intelligent-guided learning, intelligence-enhanced critical thinking, intelligence-enabled practice, and intelligent evaluation was established by West China School of Stomatology. By organically integrating technologies such as artificial intelligence, virtual simulation, and mixed reality, this system promotes a shift in the teaching paradigm from a “credit-oriented” approach to a “competency-oriented” paradigm. This transformation helps achieve seamless integration and a closed-loop process encompassing knowledge internalization, clinical reasoning, skills training, and comprehensive evaluation in experimental teaching. Practice demonstrates that this system effectively enhances students' self-directed learning skills, precision in clinical operations, and interdisciplinary diagnostic reasoning, providing valuable insights and references for advancing the application of digital technologies in the training of stomatology professionals.