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基于成都市医疗保险数据库的老年痴呆患者5 年内再入院现状及其影响因素研究

5-Year Readmission Status and Risk Factors for Senile Dementia Patients: A Study Based on Chengdu Municipal Medical Insurance Database

  • 摘要:
      目的  研究成都市老年痴呆住院患者再入院现状,分析再入院的第一诊断、经济负担和影响因素。
      方法  本次研究对象为参加了成都市城镇职工基本医疗保险(简称“城职医保”)和城乡居民基本医疗保险(简称“城居医保”),且在2013–2017年间有痴呆诊断的60岁及以上的住院患者。采用秩和检验及卡方检验分析再入院率及住院经济负担在不同特征对象中的差异,并应用logistic回归分析影响再入院的因素。
      结果  5年间老年痴呆住院患者共计27881人(78820人次),30 d内再入院率为25.14%(7011/27881),5年内再入院率为45.79%(12767/27881)。12767名再入院患者的再入院第一诊断主要包括痴呆(28.58%)、循环系统(24.26%)和呼吸系统疾病(23.71%)。再入院患者的住院经济负担高于非再入院的患者(Z=33.777,P<0.001)。再入院的发生与高龄〔以60~64岁组为参照,70~74岁组的比值比(odds ratio, OR)=1.123,95%置信区间(confidence interval, CI):1.019~1.237;75~79岁组的OR=1.108,95%CI:1.007~1.218〕、参加城职医保(OR=1.674,95%CI:1.578~1.775)、痴呆类型(以未特指的痴呆为参照,阿尔茨海默病性痴呆组:OR=1.256,95%CI:1.163~1.357;帕金森氏病性痴呆组:OR=1.774,95%CI:1.658~1.898;混合多种痴呆组:OR=1.750,95%CI:1.457~2.103)、患病情况(以只患有痴呆为参照,患有其他疾病组:OR=0.536,95%CI :0.493~0.583)、住院天数长(OR=1.593,95%CI:1.552~1.635)和医院等级低(以三级医院为参照,二级医院的OR=1.319,95%CI:1.248~1.395;一级医院的OR=1.744,95%CI:1.608~1.891;其他医院的OR=1.465,95%CI:1.311~1.637)有关。
      结论  老年痴呆患者30 d内再入院率高,再入院患者住院经济负担大。参加医保的人群中,高龄、参加城职医保、阿尔茨海默病性痴呆、帕金森氏病性痴呆、混合多种痴呆、未合并其他疾病的痴呆、住院天数长、住院医院等级低与再入院的发生相关,具体机制尚需进一步研究,以期减少老年痴呆患者再入院的发生,从而减轻疾病经济负担。

     

    Abstract:
      Objective  To study the status quo of the readmission of senile dementia patients in Chengdu, and to analyze the primary diagnosis, the economic burden and the influencing factors of readmission.
      Methods  Dementia inpatients aged 60 and above in Chengdu were the subjects of this study. The subjects were diagnosed with dementia between 2013 and 2017. Their heath insurance coverage was either the basic medical insurance for urban employees in Chengdu or the basic medical insurance for urban and rural residents of Chengdu. The rank sum test and the chi-square test were conducted to analyze the differences in readmission rate and the economic burden of hospitalization among subjects with different characteristics. Logistic regression was done to analyze the factors affecting readmission.
      Results  The total number of dementia inpatients over the 5-year period was 27881 patients (78820 admissions). The 30-day readmission rate was 25.14% (7011/27881) and the 5-year readmission rate was 45.79% (12767/27881). The primary diagnoses of 12767 readmitted patients mainly included dementia (28.57%), circulatory system diseases (24.26%), and respiratory system diseases (23.71%). The economic burden of hospitalization was higher for readmitted patients than that of patients who were not readmitted (Z=33.777, P<0.001). The occurrence of readmission was correlated to the following factors, advanced age (compared to that of the 60-65 yr. group, the 70-75 yr. group: odds ratio OR=1.123, 95% confidence interval CI: 1.019-1.237, and the 75-80 yr. group: OR=1.123, 95% CI: 1.108-1.218), participation in the basic medical insurance for urban employees (OR=1.674, 95% CI: 1.578-1.775), types of dementia (compared to unspecified dementia, Alzheimer's dementia group: OR=1.256, 95% CI: 1.163-1.357, Parkinson's disease dementia group: OR=1.774, 95% CI: 1.658-1.898, and mixed-type dementia group: OR=1.750, 95% CI: 1.457-2.103), disease condition (compared with patients with only dementia, those who have other diseases: OR=0.536, 95% CI : 0.493-0.583), length of hospital stay (OR=1.593, 95% CI: 1.552-1.635), and staying at a lower level hospital (compared to that of tertiary hospitals, secondary hospitals: OR=1.319, 95% CI: 1.248-1.395, primary hospitals: OR=1.744, 95% CI: 1.608-1.891, and other hospitals: OR=1.465, 95% CI: 1.311-1.537).
      Conclusion  Senile dementia patients have a high 30-day readmission rate, and the readmission entails heavy economic burdens on the patients. For the populations covered by medical insurance, the following features are correlated to the occurrence of readmission: advanced age, coverage by the basic medical insurance for urban employees, Alzheimer's dementia, Parkinson's disease dementia, mixed-type dementia, dementia patients without other comorbidities, extended length of stay, and hospitalization at a lower level hospital. However, further research is needed for better understanding of the specific mechanisms so that readmission of senile dementia patients can be reduced and the economic burden of the disease can be minimized.

     

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