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妊娠期糖尿病诊疗现状与进展——美国糖尿病学会《糖尿病诊疗标准(2025)》相关内容浅析

Current Status and Advances in the Diagnosis and Management of Gestational Diabetes Mellitus: An Analysis of Relevant Contents in the American Diabetes Association Standards of Care in Diabetes—2025

  • 摘要: 妊娠期糖尿病(gestational diabetes mellitus, GDM)与母儿短期及长期不良结局密切相关。近年来,随着全球肥胖和2型糖尿病(type 2 diabetes mellitus, T2DM)发病率持续上升,GDM的发生率显著增加,且地区间差异显著。GDM管理目前面临早期筛查识别不足、个体化干预策略有限以及长期随访依从性不佳等挑战。针对高危人群优化筛查方法、加强生活方式精准干预,以及健全有效随访与长期健康管理体系,是未来研究的重点方向。2024年12月,美国糖尿病学会(American Diabetes Association, ADA)发布《糖尿病诊疗标准(2025)》〔以下简称ADA(2025)〕,更新了糖尿病的诊疗观点,对GDM的定义、筛查与诊断、管理策略等方面进行总结。本文基于ADA(2025),结合我国临床实践,综述了GDM的最新进展,旨在完善GDM全程管理体系,以期避免、延缓与改善相关不良转归。

     

    Abstract: Gestational diabetes mellitus (GDM) is closely associated with short-term and long-term adverse outcomes for both mothers and fetuses. In recent years, with the global prevalence of obesity and type 2 diabetes mellitus (T2DM) constantly rising, there is a significant increase in GDM incidence, with notable regional variations. Current challenges in GDM management include insufficient early screening or diagnosis, limited personalized intervention strategies, and poor adherence to long-term follow-up. Key research priorities for the future include optimizing screening methods for high-risk populations, enhancing targeted lifestyle interventions, and establishing effective follow-up and long-term health management systems. In December 2024, the American Diabetes Association (ADA) released the Standards of Care in Diabetes—2025 (hereafter referred to as ADA 2025), providing updated perspectives on the diagnosis and treatment of diabetes mellitus, as well as an overview of the definition, screening and diagnostic criteria, and management strategies for GDM. Based on ADA (2025) and the circumstances of clinical practice in China, we summarized the latest advancements in GDM research, aiming to improve comprehensive management strategies to prevent, delay, and improve adverse outcomes associated with GDM.

     

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